Journal: Frontiers in Veterinary Science
Article Title: Breath-by-breath assessment of acute pulmonary edema using electrical impedance tomography, spirometry and volumetric capnography in a sheep ( Ovis Aries ) model
doi: 10.3389/fvets.2024.1402748
Figure Lengend Snippet: (A–E) Graphical representation of the mean variables from 15 sheep, expressed as a percentage of baseline (average of the measurements recorded 60 s prior to xylazine injection). The mean of variables recorded at each breath during xylazine injection and following injection are presented. Significant change from baseline for each specific variable ( p < 0.05) is represented by an asterix (*). The shaded area represents the 60 s that xylazine is injected. (A) Presents EIT variables including tidal impedance variation (TIV), center of ventilation ventral to dorsal (CoV VD), End expiratory lung impedance (EELI), Non-dependent silent space (NSS) and dependent silent spaces (DSS). (B) Presents EIT variables including regional ventilation in dependent ie ventral (∆ZV) centro-ventral (∆ZCV) lung regions and non-dependent lung regions ie centro-dorsal (∆ZCD) and dorsal (∆ZD). (C) Presents the airway dead space (VDaw) physiological dead space (VDBohr), alveolar ventilation (VTalv) and carbon dioxide elimination (VCO2br; PĒCO2) calculated using volumetric capnography. (D) Presents slopes of phase II (SII) and III (SIII), X interface of slope II (Xint), Y interface of slope III (Yint) and alpha angle of the volume capnograph. (E) Presents lung mechanics including dynamic airway compliance (Cdyn), peak expiratory flow (PEF), Peak inspiratory pressure (PIP) and Airway resistance (Raw).
Article Snippet: Respiratory mechanics were calculated using Flow Tool physiological waveform viewer (flowtool-2910, Respironics Nova Metrix).
Techniques: Injection